Table 5.
Cognitive and Neuropsychiatric Test Performance in the Former NFL Players and Controls
| Former NFL Players (n = 65–66)* | Controls (n = 21) | P-value | |
|---|---|---|---|
| Cognitive Function, mean (SD) T-score | |||
| NAB List Learning Delayed Recall | 41.92 (13.77) | 50.38 (12.64) | 0.0415 |
| Trail Making Test Part B | 45.12 (15.01) | 52.14 (15.45) | 0.1076 |
| Neuropsychiatric Status | |||
| CES-D, mean (SD) raw score | 21.14 (13.76) | 3.71 (4.15) | <0.0001 |
| BRIEF-A BRI, mean (SD) T-score | 62.62 (11.49) | 47.24 (9.43) | <0.0001 |
Note. The control group was required to be asymptomatic and have no history of head trauma at the time of recruitment. Mixed-effect models controlling for age and body mass index compered the former NFL players and controls on each of the clinical measures.
The sample size was reduced to 66 former NFL players due to exclusion of two participants for evidence of intentional symptom exaggeration; sample size for TMT B was further reduced to 65 former NFL players due to missing data.
Abbreviations: NAB: Neuropsychological Assessment Battery; CES-D: Center for Epidemiologic Studies Depression Scale; BRIEF-A: Behavior Rating Inventory of Executive Function-Adult version; BRI: Behavioral Regulation Index