Table 5.
Independent predictors for Clostridium difficile infection
| Step | Variable | Adjusted OR (95% CI)a | Adjusted p value | Cumulative R2 |
|---|---|---|---|---|
| 1 | Injury Severity Score | 1.99 (1.62–2.24) | < 0.01 | 0.196 |
| 2 | IV PPIs | 1.24 (1.10–1.54) | < 0.01 | 0.231 |
| 3 | Third-generation cephalosporin | 1.28 (1.07–2.01) | < 0.01 | 0.285 |
| 4 | Colonic injury | 3.52 (1.08–15.32) | < 0.01 | 0.304 |
| 5 | Clindamycin | 19.80 (4.96–31.34) | < 0.01 | 0.329 |
| 6 | Spinal injury | 41.46 (5.39–47.06) | < 0.01 | 0.384 |
| 7 | Operating room for trauma | 9.41 (2.29–38.78) | 0.02 | 0.406 |
| 8 | Admission WBC | 8.17 (1.65–23.10) | 0.012 | 0.456 |
| 9 | Fourth-generation cephalosporin | 4.65 (1.07–20.32) | 0.041 | 0.487 |
a
Area under the curve (95% CI): 0.97 (0.94–0.99), p < 0.001.
CI = confidence interval; IV PPIs = intravenous proton pump inhibitors; OR = odds ratio; WBC = white blood cell count.