Table 2.
Thalassemia genes | Number of allele | Gene frequency | 95% CI | Incidence of thalassemia | |||
---|---|---|---|---|---|---|---|
This study | Lower Northern Thailand (16) | Northern Thailand (17) | Central Thailand (18) | ||||
SEA deletion | 11 | 0.0157 | 0.008–0.028 | 3.1 | 5.2 | 6.7 | 4.6 |
3.7 deletion | 88 | 0.1257 | 0.102–0.152 | 25.1 | 19.4* | 18.6 | 17.2* |
-α4.2 deletion | 3 | 0.0043 | 0.001–0.012 | 0.8 | 0.8 | ||
Hb Constant Spring | 19 | 0.0271 | 0.016–0.042 | 5.4 | 5.2 | 4.4 | 5.6 |
Hb Paksé | 5 | 0.0071 | 0.002–0.017 | 1.4 | 0.5 | 0 | 0.5 |
Hb E | 137 | 0.1957 | 0.167–0.227 | 39.1 | 22.9 | 11.5 | 22.7 |
β-thalassemia | 2 | 0.0028 | 0.0003–0.0102 | 0.6 | 0.5 | 0.8 | 0.7 |
Combined α+ -thalassemia (-α3.7 and -α4.2)