Table 3.
Pathways significantly altered in ileum of wild type and TLR4ΔIEC mice
| Pathway Name | p-value |
|---|---|
| WebGestalt analysis | |
| DNA replication | 0.0087 |
| PPAR signaling pathway | 0.0087 |
| Fructose and mannose metabolism | 0.0391 |
| Vitamin digestion and absorption | 0.0391 |
| Pathway Express analysis | |
| Circadian rhythm | 0.00008 |
| DNA replication | 0.00081 |
| PPAR signaling pathway | 0.00156 |
| Base excision repair | 0.02190 |
| Ingenuity Pathway analysis | |
| Cell Cycle Control of Chromosomal Replication | 0.00004 |
| LPS/IL-1 Mediated Inhibition of RXR Function | 0.00417 |
| Retinol Biosynthesis | 0.00912 |
| Antigen Presentation Pathway | 0.01202 |
| Bupropion Degradation | 0.02042 |
| Estrogen Biosynthesis | 0.02399 |
| Glutathione-mediated Detoxification | 0.02399 |
| PPARα/RXRα Activation | 0.02692 |
| Acetone Degradation I (to Methylglyoxal) | 0.02692 |
| Renal Cell Carcinoma Signaling | 0.03090 |
| Adenosine Nucleotides Degradation II | 0.03981 |
| Glucocorticoid Biosynthesis | 0.03981 |
| Mineralocorticoid Biosynthesis | 0.03981 |
| Interferon Signaling | 0.04266 |
| RAR Activation | 0.04571 |
| Maturity Onset Diabetes of Young (MODY) Signaling | 0.04786 |