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. 2018 Jun 15;18(3):191–198. doi: 10.1007/s40268-018-0237-9

Table 2.

Details of octreotide therapy

Case Indication for octreotide Age at start of treatment (days) Duration of treatment (days) Route and frequency Duration of drainage Initial dose Days to initiate octreotide after effusion Maximum dose Adverse effects Response
1 Chylothorax [acquired]
Bilateral
21 22 Intravenous continuous infusion 28 1 µg/kg/h 6 10 µg/kg/h a. Transient decrease in thyroid-stimulating hormone
b. Transient hyperglycaemia
Yes
2 Chylothorax [acquired]
Bilateral
18 23 Intravenous continuous infusion 26 1 µg/kg/h 4 10 µg/kg/h a. Transient decrease in free thyroxine
b. Transient hyperglycaemia
No
3 Chylous ascites [acquired] 82 7 Intravenous continuous infusion 27 1 µg/kg/h 20 4 µg/kg/h No adverse effect Yes
4 Chylothorax [acquired]
Bilateral
72 26 Intravenous continuous infusion 53 1 µg/kg/h 27 10 µg/kg/h a. Transient hyperglycaemia
b. Transient decrease in free thyroxine and thyroid-stimulating hormone
Yes
5 Chylothorax [congenital]
Bilateral
17 9 Intravenous continuous infusion 25 1 µg/kg/h 18 10 µg/kg/h a. Decrease in free T4 No
6 Chylothorax
[acquired] Unilateral left
16 13 Intravenous continuous infusion 12 1 µg/kg/h 8 4 µg/kg/h a. Transient hyperglycaemia Yes
7 Chylothorax [congenital]
Bilateral
25 29 Intravenous continuous infusion 65 1 µg/kg/h 24 8 µg/kg/h No adverse effect No
8 Chylous ascites [congenital] 21 28 Intravenous continuous infusion 42 1 µg/kg/h 16 8 µg/kg/h a. Transient hyperglycaemia No
9 Chylothorax [acquired]
Bilateral
68 66 Intravenous continuous infusion 57 1 µg/kg/h 22 8 µg/kg/h a. Transient hyperglycaemia No
10 Chylothorax [idiopathic]
Unilateral left
64 10 Subcutaneous injection in three divided doses 40 25 µg/kg/day 13 117 µg/kg/day a. Decrease in free thyroxine and thyroid-stimulating hormone No
11 Chylothorax [congenital]
Unilateral right
24 5 Subcutaneous injection in three divided doses 23 11 µg/kg/day 10 24 µg/kg/day No adverse effects No