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. 2018 Sep 10;8:13556. doi: 10.1038/s41598-018-31710-0

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Stimulation of intra-oral receptive fields in somatosensory cortex (S1). (a) Stimulated area of an anaesthetized rat. The lower lip or tongue was stimulated with an air puff generated by a computer-triggered airflow controller. (b) Representative voltage trace (V_m) from a whole-cell patch clamp recording from an S1 cortical neuron during current injection (I_inj). (c,d) Example whole-cell recordings from a representative S1 cortical neuron showing a single trial response (top) and averaged response (bottom; n = 19 trials) to air puff stimulation of the lower lip (c) or tongue (d). Timing of stimulus delivery is indicated below each trace.