Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 10;8:13551. doi: 10.1038/s41598-018-31853-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

(A) Induction of Fgfr1, Fgfr2, and Fgfr3 by Runx2 in vitro. RNA was extracted from wild-type osteoblast progenitors that had been infected with an adenovirus expressing type II Runx2 and EGFP or EGFP alone. Samples were harvested 12 and 24 hrs after infection. Values in cells infected with the EGFP-expressing adenovirus were defined as 1, and the relative levels are shown. Data are the mean ± SD of 4 wells. **p < 0.01. (B) Suppression of Fgfr1, Fgfr2, and Fgfr3 expression by Runx2 siRNA. Osteoblast progenitors were prepared from the calvariae of wild-type newborn mice, and transfected with Runx2 siRNA. RNA was extracted 48 hours after transfection, and real-time RT-PCR was performed. Values in siRNA for the control were defined as 1, and the relative levels are shown. Data are the mean ± SE of 3 wells. **p < 0.01. Similar results were obtained in three independent experiments and representative data are shown.