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. 2018 Sep 10;9:3667. doi: 10.1038/s41467-018-06027-1

Fig. 8.

Fig. 8

Mutation signatures, somatic CNA/LOH and mutation profiles for identified SMGs in cSCC tumour samples in SCC cell lines. a Mutation signatures across all SCC cell lines. Again, signature 7 and 32 were the most dominant signatures. IC immunocompetent, IS immunosuppressed, Aza confirmed azathioprine exposure, NC no confirmed azathioprine exposure, SE sun exposed site, U unknown if sun exposed site b OncoPrint of copy gain, loss and CN-LOH segments. c Mutation OncoPrint for 22 SMGs detected in cSCC tumour samples across cell lines, ordered by aberration frequency. d Mutation OncoPrint for WD/MD/PD driver genes detected in cSCC tumour samples across cell lines, ordered by frequency. MD/PD-specific genes found in cSCC samples are highlighted in orange