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. 2018 Aug;7(4):450–463. doi: 10.21037/tlcr.2018.05.14

Table 1. Cases of East Asian patients with squamous cell carcinoma harboring ALK/ROS1 fusions.

Author Year Race Gender Age (years) Pathology Smoking status Stage Molecular alteration treatment Best response PFS (months) Reference
Wang et al. 2014 Chinese Female 55 SQCC Never IV ALK fusion Crizotinib Partial response 5.8+ (118)
Zhang et al. 2015 Chinese Female 55 SQCC Never IV ALK fusion Crizotinib Partial response 6 (119)
Wang et al. 2016 Chinese Female 37 SQCC Never IIIB ALK fusion Crizotinib Partial response 9+ (120)
Mamesaya et al. 2017 Japanese-Brazilian Female 52 SQCC Never IV ALK fusion Alectinib Partial response 11+ (121)
Li et al. 2017 Chinese Female 47 SQCC Never IV ALK-ROS1 fusion Crizotinib Partial response 5 (122)
Tamiya et al. 2015 Japanese Male 78 SQCC Ever Unknown ALK fusion Alectinib Stable disease 1.5+ (123)

PFS, progression-free survival; SQCC, squamous cell carcinoma.