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. 2018 Sep 4;9:2008. doi: 10.3389/fimmu.2018.02008

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Copyright © 2018 Avendaño-Ortiz, Maroun-Eid, Martín-Quirós, Lozano-Rodríguez, Llanos-González, Toledano, Gómez-Campelo, Montalbán-Hernández, Carballo-Cardona, Aguirre and López-Collazo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Levels of both sPD-L1 in sera and PD-L1 on CD14⁺ cells correlate with oxygen saturation in patients with sepsis. (A) Concentrations of sPD-L1 were quantified in sera from patients with sepsis (n = 85) by ELISA. The correlation between sPD-L1 and levels of oxygen saturation is shown. (B) Percentages of PD-L1⁺ cells gated on CD14⁺ cells from patients with sepsis (n = 62) were analyzed by FACS. The correlation between PD-L1 and levels of oxygen saturation is shown. ^*p < 0.05 using Spearman's test.