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. 2018 Aug 29;38(4):BSR20171713. doi: 10.1042/BSR20171713

Figure 6. APOL1 risk variants enhance ER stress.

Figure 6

Cell lysates were collected from differentiated HPs (APOL1-Vec/HPs, G0/HPs, G1/HPs, and G2/HPs), and were subjected to Western blotting to detect the expression of GRP78 and p-eIF-2α. β-actin was used as an internal loading control. Representative gels are shown in (A). The protein bands were scanned and the acquired images were analyzed using the public domain NIH image program for data quantitation. Expression of GRP78 (B) and p-eIF-2α (C) were normalized to β-actin. Data are presented as fold of control expression. *P<0.05 in comparison with control (vector), and #P<0.05 in comparison with APOL1-G0.