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. 2018 Aug 29;38(4):BSR20180547. doi: 10.1042/BSR20180547

Figure 5. miR-216a is regulated by STAT3.

Figure 5

(A) Schematic diagram of STAT3 binding sites on the promoter of miR-216a. (B) The expression of STAT3 in SKOV3 cells transfected with vector or STAT3 expression plasmid. (C) The expression of miR-216a in SKOV3 cells transfected with vector or STAT3 overexpression plasmid. (D) Luciferase assays for miR-216a promoter (wild-type or mutant) activity. The promoter constructs were co-transfected with PTEN expressing plasmid. (E) The expression of PTEN in SKOV3 cells transfected with vector or STAT3 expression plasmid. ***P<0.001. ns, not significant.