Table 2. Laboratory findings of the six families and three patients with HPP.

	FM1-1	FM1-2	FM2-1	FM2-2	FM3-1	FM4-1	FM4-2	FM5-1	PA-6	PA-7	Reference value
Serum calcium (mmol/l)	2.45	2.77	2.68	2.38	2.48	2.52	NA	2.33	2.14	2.48	2.13–2.70
Serum phosphate (mmol/l)	2.03*	2.24*	1.96*	1.26†	1.89*	1.82*	NA	1.43†	1.11†	1.19†	1.29–1.94*
											0.81–1.45†
Serum ALP (U/l)	22*	29*	6*	28†	26*	17*	29†	Negative‡	23†	13†	58–400*
											30–120†
Serum 25 (OH)D (ng/ml)	NA	NA	30.7	NA	10	17.3	NA	23.3	15.9	13.7	8–50
Serum 1,25(OH)2D (pg/ml)	17.4	NA	34.29	NA	NA	NA	NA	47.37	53.87	NA	19.6–54.3
Serum iPTH (pg/ml)	8	16.6	12.6	49.2	8	54	NA	31.4	31.9	43.4	15–65
24-h urine calcium (mmol)	0.41	NA	1.60	NA	4.64	2.78	NA	3.29	6.53	3.39	2.5–7.5
Nephrocalcinosis	no	NA	no	NA	no	no	NA	no	yes	no

Abnormal results were indicated in bold. Abbreviation: NA, not available.

^*, Indicated the normal range for serum phosphate, serum ALP in patients from 2 to 18 years old are 1.29–1.94 mmol/l, 58–400 U/l.

^†, Indicated the normal range for serum phosphate, serum ALP in adult patient are 0.81–1.45, 30–120 U/l .

^‡, Phosphatase value was negative in FM5-1 after repeated measurement.