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. 2018 Sep 10;14:1176934318797351. doi: 10.1177/1176934318797351

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© The Author(s) 2018

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Original (A) annotation and (B) reannotation of the 1352 sequences according to the hierarchical levels of BL classification. BL indicates β-lactamase; MBL: metallo-β-lactamase; SBL: serine-β-lactamase; MB1: Metallo-BL subclass MB1; MB2: Metallo-BL subclass MB2; SA1: Serine-BL subclass SA1; SA2: Serine-BL subclass SA2; SD1: Serine-BL subclass SD1; SD2: Serine-BL subclass SD2; ME: Metallo-BL class ME.