Table 1.
Associations of ZWINT Expression Level With Pathological Characteristics in Cohorts 1 and 2.
| ZWINT in Cohort 1 | ZWINT in Cohort 2 | |||||
|---|---|---|---|---|---|---|
| Variable | Low (n = 28) | High (n = 42) | P Value | Low (n = 46) | High (n = 234) | P Value |
| Sex | .283 | .903 | ||||
| Male | 22 | 37 | 40 | 205 | ||
| Female | 6 | 5 | 6 | 29 | ||
| Age | .0001 | .309 | ||||
| < 51 | 6 | 28 | 21 | 126 | ||
| >51 | 22 | 14 | 25 | 108 | ||
| HBsAg | .826 | .343 | ||||
| Negative | 8 | 11 | 9 | 33 | ||
| Positive | 20 | 31 | 37 | 201 | ||
| Serum AFP | .843 | .190 | ||||
| < 20 ng/mL | 12 | 17 | 13 | 90 | ||
| >20 ng/mL | 16 | 25 | 33 | 144 | ||
| Liver cirrhosis | .023 | .143 | ||||
| No | 5 | 1 | 11 | 82 | ||
| Yes | 23 | 41 | 35 | 152 | ||
| TNM | .018 | |||||
| I | 7 | 15 | .628 | 9 | 84 | |
| II | 13 | 16 | 25 | 121 | ||
| III-IV | 8 | 11 | 12 | 29 | ||
| Child-pugh class | .222 | .587 | ||||
| A | 27 | 37 | 43 | 213 | ||
| B | 1 | 5 | 3 | 21 | ||
| Tumor size | .226 | .005 | ||||
| <5 cm | 8 | 18 | 14 | 124 | ||
| >5 cm | 20 | 24 | 32 | 110 | ||
| Tumor number | .807 | .042 | ||||
| Single | 22 | 34 | 30 | 185 | ||
| Multiple | 6 | 8 | 16 | 49 | ||
| Tumor differentiation | .595 | .330 | ||||
| Well | 1 | 2 | 2 | 25 | ||
| Moderate | 20 | 25 | 44 | 207 | ||
| Poor | 7 | 15 | 0 | 2 | ||
| Vascular invasion | .533 | .022 | ||||
| No | 8 | 15 | 11 | 98 | ||
| Yes | 20 | 27 | 35 | 136 | ||
Abbreviations: AFP, alpha fetoprotein; HBsAg, hepatitis B surface antigen; TNM, tumor-node-metastasis.
Bold-face indicate statistically significant values.