Table 2.
Univariate and Multivariate Analyses of Clinicopathological Factors Associated With OS and TTR.
| Factors | OS | TTR | ||||||
|---|---|---|---|---|---|---|---|---|
| Univariate P | Multivariate | Univariate P | Multivariate | |||||
| HR | 95% Cl | P Value | HR | 95% Cl | P Value | |||
| Sex: Male vs Female | .603 | .925 | ||||||
| Age: ≤ 51 vs > 51 | .823 | .489 | ||||||
| HBsAg: positive vs negative | .246 | .102 | ||||||
| serum AFP, ng/mL: ≤ 20 vs > 20 | <.0001 | 1.650 | 1.107-2.460 | .014 | .001 | 1.406 | 1.005 -1.966 | .047 |
| Liver cirrhosis: yes vs no | .017 | 1.663 | 1.111-2.489 | .013 | .001 | 1.897 | 1.327-2.713 | <.0001 |
| TNM: I vs II vs III-IV | <.0001 | <.0001 | ||||||
| Child-pugh: A vs B | .136 | .182 | ||||||
| Tumor size: ≤ 5 cm vs > 5cm | <.0001 | 2.545 | 1.729-3.747 | <.0001 | <.0001 | 2.034 | 1.477-2.801 | <.0001 |
| Tumor number: single vs multiple | <.0001 | 1.997 | 1.380-2.891 | <.0001 | <.0001 | 2.349 | 1.687-3.270 | <.0001 |
| Tumor differentiation: well vs moderate vs poor | .025 | .007 | ||||||
| Vascular invasion: no vs yes | .004 | .008 | ||||||
| ZWINT: low vs High | <.0001 | 0.639 | 0.424-0.964 | .033 | <.0001 | |||
Abbreviations: AFP, alpha fetoprotein; OS, overall survival; TTR, time to recurrence; ZWINT, ZW10 interactor; HR, hazard ratio; CI, confidence interval.
Bold-face indicate statistically significant values.