Table 1.
Parameters | HF | HF.LG | HF.HG | Control |
---|---|---|---|---|
(n = 6) | (n = 6) | (n = 8) | (n = 8) | |
Body weight(g) | 31.5 ± 0.9 | 30.7 ± 0.6 | 30.2 ± 0.6 | 24.1 ± 0.6* |
AUC of OGTT(mmol/l∙h) | 21.8 ± 1.2 | 19.7 ± 0.9 | 21.4 ± 1.2 | 17.5 ± 0.8* |
Pups/litter | 8.0 ± 0.6 | 6.8 ± 1.0 | 7.2 ± 0.5 | 7.0 ± 0.6 |
Uterus index (%) to body weight(%) | 0.33 ± 0.1 | 0.42 ± 0.0 | 0.29 ± 0.1 | 0.39 ± 0.0 |
Ovary index (%) to body weight(%) | 0.11 ± 0.0 | 0.13 ± 0.0 | 0.10 ± 0.0 | 0.12 ± 0.0 |
Data are expressed as means ± S.E.M (n = 6–8/group).
p < 0.05 vs. HF group. HF, high-fat diet without genistein; HF. LG, high-fat diet with low-dose genistein; HF. HG, high-fat diet with high-dose genistein; Control, normal control diet. Uterus index: weight ratio of uterus to body weight; Ovary index: weight ratio of ovaries to body weight.