Table 2.
Treatment outcomes of the different types of optic neuritis.
| – | NMOSD | MS | Idiopathic | p1 value | p2 value | p3 value |
|---|---|---|---|---|---|---|
| NMOSD&MS | NMOSD&idiopathic | MS&idiopathic | ||||
| Number of patients | 58 | 23 | 69 | – | – | – |
| Final BCVA | – | – | – | – | – | – |
| - mean Log MAR visual acuity ± SD |
1.55+-1.02 | 0,70+-0.81 | 0.51+-0.74 | <0.001 | <0.001 | 0.358 |
| - 20/20-20/60 (N, %) | 18 (31.0) | 12 (52.2) | 47 (68.1) | 0.073 | <0.001 | 0.165 |
| - 20/70-20/200 (N, %) | 5 (8.6) | 5 (21.7) | 12 (17.4) | 0.134 | 0.166 | 0.61 |
| - <20/200 (N, %) | 35 (60.3) | 6 (26.1) | 10 (14.5) | 0.001 | <0.001 | 0.262 |
| - <10/200 (N, %) | 30 (51.7) | 5 (21.7) | 6 (8.7) | 0.003 | <0.001 | 0.181 |
| - no perception of light (N, %) |
6 (10.3) | 0 (0) | 2 (2.9) | 0.062 | 0.063 | 0.59 |
| Visual acuity outcome | – | – | – | – | – | – |
| - better (N, %) | 30 (51.7) | 18 (78.3) | 49 (71.0) | <0.001 | <0.001 | 0.510 |
| - same (N, %) | 18 (31.0) | 3 (13.0) | 13 (18.8) | 0.606 | 0.101 | 0.489 |
| - worsen (N, %) | 10 (17.2) | 2 (8.7) | 7 (10.1) | 0.135 | 0.017 | 0.798 |
| Recurrent attacks in affected eye (N of attack) | 36 (62.1) | 16 (69.6) | 16 (23.2) | 0.507 | <0.001 | <0.001 |
| Recurrent attacks in fellow eye (N of attack) | 28 (48.3) | 7 (30.4) | 9 (13.0) | 0.094 | <0.001 | 0.095 |
Abbreviations: NMOSD = Neuromyelitis Optica Spectrum Disease; MS = Multiple Sclerosis. p1 = NMOSD versus MS; p2 = NMOSD versus idiopathic; p3 = MS versus idiopathic. BCVA = Best Corrected Visual Acuity; LogMAR = Logarithm of the Minimal Angle of Resolution. SD = Standard Deviation; N = Number.