Table 3.
Predictive factors analysis for good visual outcome.
| – | Final BCVA ≥20/60 N (%) |
Final BCVA<20/60 N (%) |
Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|---|---|
| Predictive Factors | Odds ratio (95%CI) | p value | Odds ratio (95%CI) | p value | ||
| Mean age at onset (years) | 40.25 | 45.64 | 1.034 (1.009-1.061) | 0.009 | 1.061(1.025-1.098) | 0.068 |
| Female:male (N) | 61:16 | 60:13 | 0.826 (0.366-1.864) | 0.645 | – | – |
| Bilaterality | 19 (50) | 19 (50) | 1.074 (0.514-2.242) | 0.849 | – | – |
| Ocular pain | 63 (48.1) | 68 (51.9) | 0.948 (0.857-2.199) | 0.744 | – | – |
| Normal disc appearance | 51 (49.0) | 53 (51.0) | 1.431 (0.714-2.859) | 0.313 | – | – |
| Abnormal disc appearance | – | – | – | – | – | – |
| - Edema | 26 (56.5) | 20 (43.5) | 0.740 (0.368-1.488) | 0.398 | – | – |
| - Disc hemorrhage | 8 (66.67) | 4 (33.33) | 0.500 (0.144-1.738) | 0.275 | – | – |
| Initial BCVA >20/60 | 27 (84.4) | 5 (15.6) | 0.136 (0.049-0.378) | <0.001 | 0.328 (0.089-1.208) | 0.024 |
| Cause of optic neuritis | – | – | – | – | – | – |
| - NMO | 18 (31.0) | 40 (69.0) | 1.959 (1.672-4.006) | 0.768 | – | – |
| - MS | 12 (25.2) | 11 74.8) | 0.961 (0.395-2.338) | 0.93 | – | – |
| - Idiopathic | 47 (68.1) | 22 (31.2) | 0.275 (0.140-0.542) | <0.001 | 2.803 (0.977-8.044) | 0.030 |
Abbreviations: BCVA = Best Corrected Visual Acuity; N = Number; NMOSD = Neuromyelitis Optica Spectrum Disease; MS = Multiple Sclerosis;