Table 4.
Predictive factor analysis for poor visual outcome.
| – | Final BCVA<20/200 N (%) |
Final BCVA≥20/200 N (%) |
Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|---|
| Predictive factors | Odds ratio (95%CI) |
p value | Odds ratio (95%CI) | p value | ||
| Mean age at onset (years) | 45.19 | 41.87 | 0.981 (0.956-1.007) | 0.153 | – | – |
| Female:male (N) | 45:5 | 76:24 | 2.944 (1.05-8.255) | 0.040 | 0.714 (0.171-2.981) | 0.644 |
| Bilaterality | 18 (47.7) | 20 (52.3) | 0.464 (0.218-0.988) | 0.040 | 0.435 (0.171-1.111) | 0.082 |
| Ocular pain | 17 (37.0) | 29 (63.0) | 0.829 (0.401-1.712 | 0.611 | – | – |
| Normal disc apperance | 38 (36.5) | 66 (63.5) | 0.757 (0.360-1.592) | 0.463 | – | – |
| Abnormal disc appearance | – | – | – | – | – | – |
| - Edema | 13 (28.2) | 33 (71.7) | 1.321 (0.628-2.779) | 0.463 | – | – |
| - Disc hemorrhage | 4 (33.3) | 8 (66.7) | 1.175 (0.344-4.018) | 0.797 | – | – |
| Initial BCVA <20/200 | 44 (46.8) | 50 (53.2) | 0.162 (0.067-0.395) | 0.000 | 0.178(0.068-0.462) | 0.009 |
| Cause of optic neuritis | – | – | – | – | – | – |
| - NMO | 35 (60.3) | 23 (39.7)) | 0.138 (0.065-0.294) | 0.000 | 0.148 (0.067-0.330) | 0.001 |
| - MS | 6 (26.1) | 17 (73.9) | 1.555 (0.572-4.223) | 0.387 | – | – |
| - Idiopathic | 10 (14.5) | 59 (85.5) | 6.047 (2.716-13.450) | 0.879 | – | – |
Abbreviations: BCVA = Best Corrected Visual Acuity; N = Number. NMOSD = Neuromyelitis Optica Spectrum Disease; MS = Multiple Sclerosis.