Figure 6. Comparison of 20-HETE receptor antagonist and ARB - late treatment.

Time course of SBP (A) and albuminuria (B), and the data for left ventricle weights normalized by tibial length (C) and glomerulosclerosis index (D) in I3C-induced and non-induced Cyp1a1-Ren-2 transgenic rats, and effects of 20-HETE antagonist or AT₁ receptor antagonist treatment started during established hypertension (‘late treatment protocol’). *P<0.05 compared with basal values (or compared with non-induced rats in the case of left ventricle weights and glomerulosclerosis index). n=6–8 per group. ^#P<0.05 compared with * marked values at the same time point (or compared with all other groups of rats in the case of left ventricle weights and glomerulosclerosis index).