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. 2018 Aug 16;18(4):3611–3618. doi: 10.3892/mmr.2018.9392

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Copyright: © Ye et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — CCl₄ treatment aggravates hepatic necrosis in Glt25d1^+/− mice. Representative micrographs of HE-stained liver sections from (A) WT and (B) Glt25d1^+/− groups treated with corn oil and (C) WT and (D) Glt25d1^+/− groups treated with CCl₄. Arrows indicate necrotic areas (magnification, ×100). (E) Necrotic area percentages. Changes in serum (F) ALT and (G) AST levels in CCl₄- and corn oil-treated mice. Data are expressed as the mean ± standard deviation (n=6–8). **P<0.01, ***P<0.001; significance determined by Student's t-test or two-way analysis of variance followed by Tukey's test. Glt25d1, collagen β (1-O) galactosyltransferase 1; CCl₄, carbon tetrachloride; ALT, alanine aminotransferase; AST, aspartate aminotransferase; WT, wild-type.