Table III.
Functions enriched for the genes involved in the 4 modules.
| Module | Adjusted P-value | Gene number | Description | Gene symbol |
|---|---|---|---|---|
| Module A | 2.07E-02 | 2 | GO:6511~ubiquitin-dependent protein catabolic process | CUL4A, DDB1 |
| 2.07E-02 | 2 | GO:19941~modification-dependent protein catabolic process | CUL4A, DDB1 | |
| 2.07E-02 | 2 | GO:6281~DNA repair | CUL4A, DDB1 | |
| 2.07E-02 | 2 | GO:44257~cellular protein catabolic process | CUL4A, DDB1 | |
| 2.93E-02 | 1 | GO:718~nucleotide-excision repair, DNA damage removal | DDB1 | |
| 3.40E-02 | 2 | GO:33554~cellular response to stress | CUL4A, DDB1 | |
| 4.43E-02 | 2 | GO:6508~proteolysis | CUL4A, DDB1 | |
| 4.58E-02 | 2 | GO:44248~cellular catabolic process | CUL4A, DDB1 | |
| 4.58E-02 | 2 | GO:51704~multi-organism process | CUL4A, DDB1 | |
| Module B | 4.33E-02 | 1 | GO:35408~histone H3-T6 phosphorylation | PRKCA |
| 4.33E-02 | 1 | GO:35405~histone-threonine phosphorylation | PRKCA | |
| 4.33E-02 | 1 | GO:46325~negative regulation of glucose import | PRKCA | |
| 4.33E-02 | 1 | GO:51965~positive regulation of synaptogenesis | PRKCA | |
| 4.33E-02 | 2 | GO:42330~taxis | PRKCA, SCRIB | |
| 4.33E-02 | 2 | GO:6935~chemotaxis | PRKCA, SCRIB | |
| 4.33E-02 | 1 | GO:32863~activation of Rac GTPase activity | SCRIB | |
| 4.33E-02 | 1 | GO:60561~apoptosis involved in morphogenesis | SCRIB | |
| 4.33E-02 | 1 | GO:1921~positive regulation of receptor recycling | SCRIB | |
| 4.33E-02 | 1 | GO:35089~establishment of apical/basal cell polarity | SCRIB | |
| Module C | 2.52E-02 | 1 | GO:7088~regulation of mitosis | ANAPC10 |
| 2.52E-02 | 1 | GO:51783~regulation of nuclear division | ANAPC10 | |
| 2.19E-03 | 1 | GO:8054~cyclin catabolic process | ANAPC2 | |
| 7.21E-03 | 1 | GO:45773~positive regulation of axon extension | ANAPC2 | |
| 8.55E-03 | 1 | GO:48814~regulation of dendrite morphogenesis | ANAPC2 | |
| 9.45E-03 | 1 | GO:48639~positive regulation of developmental growth | ANAPC2 | |
| 3.37E-02 | 1 | GO:10720~positive regulation of cell development | ANAPC2 | |
| 3.38E-02 | 1 | GO:45927~positive regulation of growth | ANAPC2 | |
| 4.13E-02 | 1 | GO:10975~regulation of neuron projection development | ANAPC2 | |
| 4.89E-02 | 1 | GO:31344~regulation of cell projection organization | ANAPC2 | |
| 9.69E-03 | 2 | GO:51726~regulation of cell cycle | ANAPC2, ANAPC10 | |
| 1.33E-02 | 2 | GO:51128~regulation of cellular component organization | ANAPC2, ANAPC10 | |
| Module D | 3.15E-02 | 1 | GO:45~autophagic vacuole assembly | MAP1LC3A |
| 3.15E-02 | 1 | GO:16236~macroautophagy | MAP1LC3A | |
| 4.65E-02 | 1 | GO:6914~autophagy | MAP1LC3A | |
| 4.65E-02 | 1 | GO:9267~cellular response to starvation | MAP1LC3A | |
| 4.65E-02 | 1 | GO:7033~vacuole organization | MAP1LC3A |
GO, gene ontology.