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. 2018 Apr 13;16(10):1756–1766. doi: 10.1111/pbi.12912

Figure 1.

Figure 1

Substrates involved in caffeine biosynthesis pathways and its other related pathways catalysed by enzymes that were encoded by genes carrying the TAVs identified from this study. (a) The SAM (S‐adenosyl‐Lmethionine) cycle (the activated methyl cycle) in plants (adapted from Ashihara and Suzuki, 2004); (b) the biosynthetic pathways of caffeine from xanthosine (adapted from Ashihara et al., 2011b); (c) the ‘provider pathways’ for xanthosine synthesis in purine alkaloid forming plants (adapted from Ashihara and Suzuki, 2004); (d) de novo biosynthetic pathway of IMP in plants (adapted from Ashihara and Suzuki, 2004); circles: location of substrates/precursors, which were formed in the KEGG pathways catalysed by enzymes encoded by genes carrying the TAVs identified from this study. Circles of the same colour indicated the alternative locations of the same substrate.