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. 2018 Sep 10;8:13557. doi: 10.1038/s41598-018-31740-8

Table 2.

Dose prediction of candidate protein markers.

Modela Predicted dose (Mean ± SD, Gy) coefficient b R2
(p value)b
MAEc
Actual irradiated dose
0 Gy 1 Gy 2 Gy
Dose ~ FDXR + ACTN1 0.003 ± 0.050 1.06 ± 0.17 1.90 ± 0.24 0.95 ± 0.06 0.958 (<0.0001) 0.13
Dose ~ FDXR + ACTN1 + DDB2 0.001 ± 0.034 1.06 ± 0.14 1.91 ± 0.26 0.96 ± 0.06 0.959 (<0.0001) 0.12
Dose ~ FDXR + ACTN1 + BAX 0.001 ± 0.046 1.07 ± 0.16 1.90 ± 0.23 0.95 ± 0.06 0.958 (<0.0001) 0.13
Dose ~ FDXR + ACTN1 + DDB2 + BAX 0.13 ± 0.20 1.05 ± 0.14 1.91 ± 0.26 0.90 ± 0.06 0.942 (<0.0001) 0.15

aData obtained from proteomic analysis were used for investigating dose prediction. Ranks and specific values of all models were provided in Supplementary Table S4.

bCoefficient, R2 and p value was obtained by linear regression analysis for predicted vs. actual doses.

cMAE values were used as indicators to compare the difference between actual irradiated and predicted dose.