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. 2018 Sep 4;9:2081. doi: 10.3389/fmicb.2018.02081

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Copyright © 2018 Wu, Zheng, Zhang, Pang, Li, Wang, Yang, Wu, Tang, Tang and Liang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of P. gingivalis infection on expression of FASN and ACC1 in tongue tissues of 4NQO-treated mice. IHC analyses were performed in tongue tissues from each experimental group following the procedures described in Section “Materials and Methods.” Representative photographs for FASN (A) and ACC1 (B) were showed and at least five mice from each experimental group with two images per mouse were quantified. These results revealed that greater levels of FASN and ACC1 in 4NQO + P.g group than in 4NQO group. All images were taken at 400× magnification. Each column represents the mean ± SD; ^∗P < 0.05; ^∗∗P < 0.001. (C) Graphics of mRNA expression levels of FASN and ACC1 by RT-qPCR for samples from each experimental group. The columns represent the mean ± SEM of five animals per group; ^∗∗P < 0.001.