Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 4;9:1994. doi: 10.3389/fimmu.2018.01994

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Li, Huang, Jiang, Chen, Zhang, Wei, Chen, Lian, Bian, Miao, Peng, Fang, Wang, Tang, Gershwin and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

MAIT cell percentages among circulating CD3⁺ T cells in HC and NAFLD patients, as well as correlations between circulating MAIT cell percentage and clinical parameters in NAFLD patients. (A) Representative flow cytometry scatter plots from HC and NAFLD patient (Left panel). CD3⁺CD161^highVα7.2⁺ cells were confirmed by MR1-5-OP-RU TEM and MR1-6-FP TEM (negative control) (Right panel). (B) Statistical analysis of circulating MAIT cell frequency in HC (n = 48) and patients with NAFLD (n = 60). Spearman correlation between MAIT frequency with (C) HbA1c (n = 47) and (D) BMI (n = 60) in NAFLD patients. (E,F) NAFLD patients with higher serum GGT or TG (> 2 × ULN) had lower peripheral MAIT cell percentage than those patients with lower (< 2 × ULN) GGT or TG. Data were analyzed with Mann–Whitney U-tests. *P < 0.05, **P < 0.01. TEM, tetramer; BMI, body mass index; GGT, γ-glutamyl transferase; TG, triglyceride; ULN, upper limit of normal.