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. 2018 Sep 4;9:1994. doi: 10.3389/fimmu.2018.01994

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Copyright © 2018 Li, Huang, Jiang, Chen, Zhang, Wei, Chen, Lian, Bian, Miao, Peng, Fang, Wang, Tang, Gershwin and Ma.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparisons of pro-inflammatory cytokine expression and macrophages in livers between MR1^−/−-MCD mice and WT-MCD mice. (A) Hepatic expression of the TNF-α mRNA in WT and MR1^−/− mice on ND and MCD. (B) Higher total macrophage (F4/80⁺) number in liver of MR1^−/− mice on MCD compared to WT-MCD mice. Representative dot plots and the percentage of CD11c⁺ macrophages (C) and CD206⁺ macrophages (D) from individual mice in WT and MR1^−/− group on ND or MCD (n = 10). Data were analyzed using ANOVA with Bonferroni test comparison. *P < 0.05.