Table III.
Effect of ghrelin on TNF-α and NF-κB protein expression levels in the cortex of a pilocarpine-induced epileptic rat model, expressed as optical density values.
| Group | TNF-α | NF-κB |
|---|---|---|
| Normal control group | 0.175±0.032 | 0.145±0.006 |
| Pilocarpine group | 1.098±0.043a | 0.920±0.512 |
| Pilocarpine + saline group | 1.305±0.050a | 0.850±0.086 |
| Pilocarpine + ghrelin group | 0.855±0.081b | 0.265±0.023b |
a
P<0.05 vs. control group
b
P<0.05 vs. pilocarpine and pilocarpine + saline groups; n=8. TNF-α, tumor necrosis factor-α; NF-κB, nuclear factor-κB.