Table IV.
Effect of ghrelin on TNF-α and NF-κB mRNA expression levels in the cortex of a pilocarpine-induced epileptic rat model, expressed as optical density values.
| Group | TNF-α | NF-κB |
|---|---|---|
| Normal control group | 0.907±0.023 | 0.747±0.069 |
| Pilocarpine group | 1.667±0.016a | 1.907±0.075a |
| Pilocarpine + saline group | 1.684±0.032a | 1.658±0.113a |
| Pilocarpine + ghrelin group | 0.787±0.014b | 0.622±0.024b |
a
P<0.05 vs. control group
b
P<0.05 vs. pilocarpine and pilocarpine + saline groups; n=8. TNF-α, tumor necrosis factor-α; NF-κB, nuclear factor-κB.