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. 2018 Sep 4;8:361. doi: 10.3389/fonc.2018.00361

Table 1.

HLA-G expression detected with mAbs 4H84 and 5A6G7 related to the clinical parameters in CRC patients.

Variables Cases HLA-G (mAb 4H84) HLA-G(mAb 5A6G7)
Neg. Pos. (%) p* Neg. Pos. (%) p*
Gender
    Male 214 69 145 (67.8%) 0.150 95 119 (55.6%) 0.329
    Female 165 42 123 (74.5%) 65 100 (60.6%)
Age
     ≤ median (66 ys) 188 52 136 (72.3%) 0.490 78 110 (58.5%) 0.776
    >median 191 59 132 (69.1%) 82 109 (57.1%)
TNM stage
    Tumor status
    T1+2 108 26 82 (75.9%) 0.016 39 69 (63.9%) 0.110
    T3 256 79 177 (69.1%) 117 139 (54.3%)
    T4 15 6 9 (60.0%) 4 11 (73.3%)
    Nodal status
    N0 201 57 144 (71.6%) 0.870 82 119 (59.2%) 0.421
    N1 109 34 75 (68.8%) 44 65 (54.3%)
    N2 69 20 49 (71.0%) 34 35 (73.3%)
    Metastasis status
    M0 368 110 258 (70.1%) 0.135 156 212 (57.6%) 0.690
    M1 11 1 10 (90.9%) 4 7 (63.6%)
Disease stage
    I 85 23 62 (72.9%) 0.434 28 57 (67.1%) 0.207
    II 114 34 80 (70.2%) 54 60 (52.6%)
    III 169 53 116 (68.6%) 74 95 (56.2%)
    IV 11 1 10 (90.9%) 4 7 (63.6%)
*

Comparison of HLA-G expression status between or among each variable using the Pearson chi-square test. TNM, lymph-node-metastasis and stage according to the TNM classification.