Table 1.
Weight gain of dams and parameters of rat pups following prenatal exposure to deltamethrin and/or memantine.
| Control | 9 mg/kg DM | 2.7 mg/kg DM | 1.35 mg/kg DM | 0.54 mg/kg DM | 9 mg/kg DM +MEM | MEM | |
|---|---|---|---|---|---|---|---|
| Maternal weight gain during pregnancy (g) | |||||||
| Days 0–7 | 14.1 ± 3.08 | 13.71 ± 2.95 | 13.31 ± 2.79 | 13.95 ± 2.35 | 13.71 ± 2.97 | 13.32 ± 2.42 | 13.51 ± 2.42 |
| Days 7–14 | 14.76 ± 5.54 | 13.84 ± 5.51 | 13.45 ± 4.75 | 14.53 ± 5.26 | 13.01 ± 4.48 | 14.40 ± 4.47 | 14.26 ± 5.33 |
| Days 14–21 | 65.39 ± 15.2 | 63.68 ± 15.59 | 64.09 ± 14.76 | 64.33 ± 13.8 | 65.55 ± 16.48 | 65.68 ± 13.27 | 66.7 ± 16.48 |
| Overall weight gain during pregnancy (%) | 40.31 ± 6.17 | 39.08 ± 6.18 | 38.77 ± 6.03 | 39.76 ± 5.49 | 39.36 ± 4.88 | 39.96 ± 4.4 | 40.32 ± 5.98 |
| Number of litters | 6 | 6 | 6 | 6 | 6 | 6 | 6 |
| Litter size | 10.0 ± 1.41 | 8.5 ± 1.38 | 9.2 ± 1.47 | 9.7 ± 1.97 | 9.5 ± 1.87 | 9.0 ± 1.41 | 9.8 ± 1.17 |
| Live birth index (%)a | 98.3 | 98 | 100 | 98.3 | 96.5 | 98.1 | 100 |
| Weaning index (%)b | 96.7 | 98 | 96.4 | 98.2 | 100 | 100 | 96.7 |
| Body weight of pups (g) | |||||||
| PND 0 | 5.67 ± 0.41 | 5.98 ± 0.38∗∗ | 5.78 ± 0.43 | 5.61 ± 0.43 | 5.53 ± 0.45 | 5.54 ± 0.48 | 5.72 ± 0.41 |
| PND 7 | 13.53 ± 0.78 | 13.74 ± 0.75 | 13.65 ± 0.71 | 13.32 ± 0.75 | 13.53 ± 0.67 | 13.57 ± 0.74 | 13.50 ± 0.77 |
| PND 14 | 27.62 ± 1.37 | 28.12 ± 1.50 | 27.78 ± 1.49 | 27.48 ± 1.38 | 27.32 ± 1.37 | 27.38 ± 1.19 | 28.09 ± 1.62 |
| PND 21 | 57.10 ± 4.21 | 52.67 ± 4.72 | 49.73 ± 4.87 | 50.48 ± 4.40 | 49.46 ± 4.91 | 51.24 ± 4.48 | 52.00 ± 4.39 |
Values are represented as means ± SD. aLive birth index = (number of live pups on PND 0/number of pups delivered) × 100. bWeaning index = (number of live pups on PND 21/number of pups alive on PND 0) × 100. ∗∗Significantly different from control group, P-value < 0.01.