Figure 4.

SIN decreases the mRNA expression levels of TNF-α, IL-6 and iNOS. Reverse transcription-quantitative polymerase chain reaction was performed on gut homogenates to detect (A) TNF-α, (B) IL-6 and (C) iNOS. Data are represented as mean ± standard error of the mean. *P<0.05, **P<0.01 vs. control group; ^#P<0.05, ^##P<0.01 vs. DSS group. DSS, dextran sulfate sodium; IL-6, interleukin-6; iNOS, inducible nitric oxide synthase; SIN, sinomenine; SASP, salicylazosulfapyridine; SOD, superoxide dismutase; TNF-α, tumor necrosis factor-α.