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. 2018 Aug 10;18(4):3691–3698. doi: 10.3892/mmr.2018.9378

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Copyright: © Zhou et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — SIN induces the Nrf2/NQO-1 pathway in DSS-induced colitis. Western blot analysis of (A and B) nuclear Nrf2 and (C and D) cytoplasmic NQO-1 protein expression. (E) Reverse transcription-quantitative polymerase chain reaction analysis of HO-1 mRNA expression levels. Data are represented as mean ± standard error of the mean. ^#P<0.05, ^##P<0.01 vs. DSS group. DSS, dextran sulfate sodium; HO-1, heme oxygenase-1; NQO-1, NADP (H) quinone oxidoreductase 1; Nrf2, nuclear factor erythroid 2-related factor 2; SIN, sinomenine; SASP, salicylazosulfapyridine.