Table 1.
Demographic and clinical characteristics of participants.
| Characteristic |
Placebo (n = 11) |
Baclofen 30–75 mg (n = 20) |
|---|---|---|
| Age, y | 51.73 ± 12.06 | 48.65 ± 9.24 |
| Gender, % F | 46 | 25 |
| Education, y | 14.36 ± 2.63 | 14.45 ± 2.38 |
| Unemployed, % | 18 | 40 |
| Drinks per drinking daya | 12.12 ± 4.34 | 9.92 ± 5.90 |
| Years since alcohol-related problems began | 14.15 ± 9.59 | 16.23 ± 11.24 |
| Alcohol dependence severity | 13.73 ± 6.18 | 16.95 ± 8.29 |
| PACS craving | 17.91 ± 5.11 | 15.60 ± 5.62 |
| Alcoholic liver disease, % | 27 | 20 |
| Cigarette smokers, % | 73 | 75 |
| Antidepressant use, % | 82 | 60 |
Data represent mean ± SD unless otherwise noted.
a
During the 30 days preceding the first day of the study, based on the Time-Line Follow-Back method. ADS, Alcohol Dependence Severity Scale; PACS, Penn Alcohol Craving Scale. There were no significant differences between groups on baseline variables.