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. 2018 Sep 4;11:309. doi: 10.3389/fnmol.2018.00309

Figure 1.

Figure 1

Inflammasome proteins are elevated in the serum of stroke patients. (A) Protein levels in pg/ml of caspase-1 ASC, IL-1β and IL-18 analyze by with a Simple Plex system in serum samples from patients with stroke and healthy donors. p-value of significance is shown above each box plot. Box and whiskers are shown for the 5th and 95th percentile. N.S., Not Significant. Caspase-1: N = 8 control and N = 13 stroke; ASC: N = 75 control and N = 16 stroke; IL-1: N = 9 control and N = 8 stroke; and IL-18: N = 79 control and N = 15 stroke. (B) ROC curves for caspase-1 (orange), ASC (blue), IL-1β (black) and IL-18 (green). Caspase-1: N = 8 control and N = 13 stroke; ASC: N = 75 control and N = 16 stroke; IL-1: N = 9 control and N = 8 stroke; and IL-18: N = 79 control and N = 15 stroke. Dark circles correspond to data points outside the 95% confidence interval.