Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Increased resistance to sorafenib in HepG2 spheres. Spheres were treated with 5, 10, 15, 20 or 25 µM sorafenib for 48 h and the inhibition rate was calculated according to cell viability, as assessed by Cell Counting Kit-8 assay. Each experiment was repeated in triplicate and the data are expressed as the mean ± standard deviation. *P<0.05.
