Table 2.
Cases of Claisen–Schmidt Condensation for the Synthesis of Chalcones
| Entry | Catalyst | Solvent | Reaction | Ref |
|---|---|---|---|---|
| 1 | NaOH | ethanol |
|
98 |
| 2 | NaOH KOH |
methanol ethanol |
|
55,56, 99 |
| 3 | Piperazine | methanol ethanol |
|
100 |
| 4 | Ca(OH)2 Ba(OH)2 Sr(OH)2 |
aprotic solvent |
|
101 |
| 5 | LiHDMS | THF |
|
102 |
| 6 | NaNO3 (LiNO3)/natural phosphates |
methanol | 6,103 | |
| 7 | HCl | ethanol | 107 | |
| 8 | AlCl3 | carbon disulfide |
107 | |
| 9 | BF3–Et2O | dioxane | 105,110 | |
| 10 | SOCl2 | ethanol |
|
454 |
| 11 | p-TsOH | acetic acid |
|
109 |
| 12 | NaOH | / |
|
113 |
| 13 | KF-Al2O3 | / |
|
115 |
| 14 | CaO | / |
|
114 |
| 15 | TBAB | inorganic alkaline solution |
|
119 |
| 16 | hydrotalcite | [dbmin]BF4 |
|
120 |