Table 4.
Clinical characteristics of monkeys with USS0–1 or USS2–3
| Factor | All (n = 86) |
USS 2–3 (n = 25) |
USS 0–1 (n = 61) |
p-value |
|---|---|---|---|---|
| Age (years) | 18.1 ± 0.6 | 17.8 ± 0.5 | 18.2 ± 0.8 | 0.76 |
| SBP (mmHg) | 127.1 ± 2.3 | 134.3 ± 4.3 | 124.1 ± 2.6 | 0.04 |
| DBP (mmHg) | 76.4 ± 1.1 | 78.9 ± 1.9 | 75.4 ± 1.4 | 0.17 |
| BW (kg) | 12.8 ± 0.5 | 16.7 ± 1.0 | 11.2 ± 0.4 | < 0.001 |
| BMI | 17.9 ± 0.7 | 23.5 ± 1.4 | 15.6 ± 0.5 | < 0.001 |
| WC (cm) | 45.0 ± 1.5 | 56.6 ± 3.0 | 40.2 ± 1.3 | < 0.001 |
| FPG (mmol/L) | 4.6 ± 0.2 | 5.2 ± 0.6 | 4.3 ± 0.1 | 0.03 |
| HOMA IR | 6.9 ± 1.6 | 14.3 ± 5.1 | 3.9 ± 0.5 | 0.003 |
| Insulin (μU/ml) | 28.0 ± 3.9 | 50.1 ± 11.3 | 19.0 ± 2.1 | < 0.001 |
| CRP (mg/dL) | 0.3 ± 0.1 | 0.4 ± 0.1 | 0.3 ± 0.1 | 0.26 |
| TG (mmol/L) | 0.8 ± 0.1 | 1.3 ± 0.4 | 0.6 ± 0.0 | 0.005 |
| TC (mmol/L) | 4.1 ± 0.2 | 4.9 ± 0.6 | 3.8 ± 0.2 | 0.03 |
| HDL-c (mmol/L) | 1.9 ± 0.1 | 1.6 ± 0.1 | 2.0 ± 0.1 | 0.01 |
| LDL-c (mmol/L) | 2.0 ± 0.2 | 2.9 ± 0.6 | 1.7 ± 0.2 | 0.01 |
| NEFA (mmol/L) | 1.1 ± 0.1 | 1.4 ± 0.3 | 1.0 ± 0.1 | 0.10 |
| ALT (U/L) | 61.7 ± 4.0 | 65.1 ± 8.2 | 60.3 ± 4.5 | 0.59 |
| AST (U/L) | 27.4 ± 0.8 | 26.5 ± 1. | 27.7 ± 0.9 | 0.52 |
Data represented as mean ± SE; student t-test
USS ultrasonographic steatosis score, SBP systolic blood pressure, DBP diastolic blood pressure, BW body weight, BMI body mass index, WC waist circumference, FPG fasting plasma glucose, HOMA IR homeostasis model assessment of insulin resistance, CRP C-reactive protein, TG triglycerides, TC total cholesterol, HDL-c high-density lipoprotein-cholesterol, LDL-c low-density lipoprotein-cholesterol, NEFA non-esterified fatty acid, ALT alanine aminotransferase, AST aspartate aminotransferase