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. 2018 Sep 10;19:316. doi: 10.1186/s12859-018-2343-7

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Reprogrammed enhancers are prevalent in mammalian genomes. a. Average percentage of reprogrammed enhancers (RPEs), functionally conserved enhancers (FCEs) and enhancer gains (EGs) in the human genome. b. Proportion of the 3 categories of enhancers per human tissue