Table 2.
Antibacterial activities of the tested formulations (MIC)
| Formulations | MICa (µM) | |||||
|---|---|---|---|---|---|---|
| Gram-positive | Gram-negative | |||||
| S. aureus ATCC29213 | S. pneumoniae ATCC49619 | A. pyogenes ATCC19411 | E. coli ATCC25922 | P. aeruginosa ATCC27853 | S. typhimurium ATCC13311 | |
| BA solution | 2 | 4 | 4 | > 128 | > 128 | > 128 |
| Nano-BAPLGA | 1 | 2 | 2 | 16 | 32 | 32 |
| Nano-BAF127 | 0.5 | 1 | 1 | 8 | 16 | 16 |
| Nano-BAP123 | 0.5 | 1 | 1 | 4 | 8 | 4 |
| Nano-BAP85 | 0.5 | 0.5 | 1 | 1 | 2 | 2 |
| Polymyxin B | > 128 | > 128 | > 128 | 1 | 1 | 2 |
aMinimal inhibitory concentrations (MICs) were determined as the lowest concentration of the tested copolymers that inhibited bacterial growth