Table 2.
Variable | N (%) |
---|---|
Boost approach | |
SeqB | 103 (54.3) |
SIB | 87 (45.7) |
SIB dose and fractionation | |
PTV dose-tumor (Gy) | |
54 Gy/30 fractions | 57 (65.5) |
50.4 Gy/28 fractions | 30 (34.5) |
PTV dose-positive nodes (Gy) (26 pts) | |
50.4 Gy/30 fractions | 26 (100.0) |
PTV dose-negative nodes (Gy) | |
45 Gy/30 fractions | 53 (60.9) |
42 Gy/28 fractions | 34 (39.1) |
SeqB dose and fractionation | |
PTV dose-first sequence | |
36 Gy/20 fractions | 103 (100) |
PTV dose-sequential boost | |
23,4 Gy/13 fractions | 103 (100) |
Chemotherapy regimens | |
5-FU + MMC × 2 cycles | 159 (83.7) |
5-FU + MMC × 1 cycle | 2 (1.0) |
Capecitabine + MMC × 2 cycles | 26 (13.7) |
Capecitabine + MMC × 1 cycle | 3 (1.6) |
Legend, SeqB sequential boost, SIB simultaneous integrated boost, PTV planning target volume, Gy Gray, pts patients, 5-FU 5-fluorouracil, MMC mitomycin C