Table 2.
Chi-square test of re-RT and without re-RT for locoregional recurrent ESCC before and after matching
| Variables | Before matching | After matching | ||||
|---|---|---|---|---|---|---|
| With re-RT (n) | Without re-RT (n) | P | With re-RT (n) | Without re-RT (n) | P | |
| Age (years) | 1.000 | 1.000 | ||||
| < 65/≥65 | 26/13 | 32/16 | 21/12 | 21/12 | ||
| KPS | 0.770 | 0.802 | ||||
| 70–80/>80 | 15/24 | 17/31 | 13/20 | 14/19 | ||
| Gender | 0.572 | 0.580 | ||||
| Male/Female | 28/11 | 37/11 | 23/10 | 25/8 | ||
| Smoking | 0.619 | 0.796 | ||||
| Yes/No | 15/24 | 16/32 | 12/21 | 11/22 | ||
| Alcohol consumption | 0.679 | 1.000 | ||||
| Yes/No | 6/33 | 9/39 | 5/28 | 5/28 | ||
| Primary tumor location | 0.583 | 0.802 | ||||
| Upper/Middle and lower thoracic | 14/25 | 20/28 | 14/19 | 13/20 | ||
| Initial clinical stage | 0.003 | 0.284 | ||||
| I + II/III | 18/21 | 8/40 | 12/21 | 8/25 | ||
| Surgery in the initial treatment | 0.488 | 0.392 | ||||
| Yes/No | 6/33 | 5/43 | 2/31 | 4/29 | ||
| Chemotherapy in the initial treatment | 0.582 | 0.806 | ||||
| Yes/No | 18/21 | 25/23 | 16/17 | 17/16 | ||
| Radiation dose in the initial treatment (Gy) | 0.101 | 0.213* | ||||
| ≤ 50/> 50 | 8/31 | 4/44 | 5/28 | 2/31 | ||
| Recurrence-free interval (months) | 0.187 | 0.215 | ||||
| Median (range) | 27(4163) | 12.5(3168) | 27(5163) | 12(3144) | ||
| ≤ 12/> 12 | 14/25 | 24/24 | 12/21 | 17/16 | ||
Abbreviation: Re-RT Re-irradiation, KPS Karnofsky performance status. *:Fisher's exact tests