Table 4.

Cochran-Mantel-Haenszel (CMH) Mean Score Difference (F) test for the total skin lesions score, the total extent of the lesion score and the pruritus score at Day 28, Day 56 and Day 84 compared to Day 0 for 31^a dogs treated with afoxolaner who didn’t received concomitant medications for the control of skin conditions

		Day 28	Day 56	Day 84
Total skin lesion score	CMH row mean scores differ	F(1, 62) = 19.0	F(1, 63) = 38.2	F(1, 62) = 45.3
	P-value	<0.0001	<0.0001	<0.0001
Total lesion extent score	CMH row mean scores differ	F(1, 62) = 15.0	F(1, 63) = 33.0	F(1, 62) = 45.4
	P-value	<0.0001	<0.0001	<0.0001
Pruritus score	CMH row mean scores differ	F(1, 63) = 13.7	F(1, 64) = 27.6	F(1, 63) = 32.2
	P-value	0.0002	<0.0001	<0.0001

^a17 animals were excluded from the analyses because of concomitant medications for the control of skin conditions