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. 2018 Sep 10;18:250. doi: 10.1186/s12906-018-2309-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Histological evaluation of gastric epithelial dysplasia. Model gastric epithelium displayed GED pathology characterized by glandular architectural abnormalities such as splitting, elongated and crowded glands, back to back formation, as well as by cytological atypia with rounded, pleomorphic nuclei that display prominent nucleoli and loss of polarity. After WPX intervention, these GED pathological alterations, especially irregularities of glandular structure, were regressed in varying degrees. n = 9 in each group. (H&E staining, 100×)