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. 2018 Sep 10;19:317. doi: 10.1186/s12859-018-2318-8

Table 6.

Simulation study 2 with nX=nY=30 and 100 runs

Number of 1 block 2 blocks
DE genes α α
per block 0.1 0.05 0.01 0.1 0.05 0.01
5 p^m 0 0 0 0 0 0
% 100 (0) 100 (0) 100 (0) 100 (0) 100 (0) 100 (0)
20 p^m 0 0 0 0 0 0
% 100 (0) 100 (0) 100 (0) 100 (0) 100 (0) 100 (0)
100 p^m 0 0 0 0 0 0
% 100 (0) 100 (0) 100 (0) 100 (0) 100 (0) 100 (0)
Number of 3 blocks
DE genes α
per block 0.1 0.05 0.01
5 p^m 0 0 0
% 100 (0) 100 (0) 100 (0)
20 p^m 0 0 0.01
% 100 100 99.9 (0.7)
100 p^m 0 0.01 0.04
% 100 (0) 100.0 (0.0) 99.8 (1.9)

Evaluation of the first step of the ORdensity method using different values of α. The Table shows the estimated probability, p^m, of no considering as a potential DE gene at least one gene that it really is, and the mean proportion of DE genes (row named “%”) that the procedure considered as potential DE genes. Corresponding standard deviations are in brackets