Table 7.
Simulation study 2, with nX=nY=30 and 100 runs
B | DE | 10f0 | C i | |||||
---|---|---|---|---|---|---|---|---|
(sd) | (sd) | (sd) | (sd) | (sd) | ||||
27.9 | 160.4 | 6.6 | 8.1 | 32.0 | ||||
(31.2) | (102.2) | (1.1) | (10.8) | (43.9) | ||||
5 | 9.1 | C 2 | 92.1 | 10.1 | 9.0 | 24.1 | 100 | |
(25.5) | (0.8) | (0.4) | (4.0) | (0) | ||||
C 3 | 82.5 | 7.8 | 9.4 | 41.6 | 100 | |||
(17.9) | (0.3) | (0.3) | (2.2) | (0) | ||||
20.0 | 233.0 | 0.0 | 0.0 | 0.0 | ||||
(0.0) | (35.1) | (0.0) | (0.0) | (0) | ||||
1 | 20 | 9.1 | C 2 | 96.5 | 10.4 | 9.0 | 22.0 | 100 |
(12.7) | (0.5) | (0.1) | (1.5) | (0) | ||||
C 3 | 90.1 | 7.7 | 9.2 | 41.1 | 100 | |||
(14.2) | (0.2) | (0.1) | (1.4) | (0) | ||||
100.0 | 209.5 | 0.0 | 0.0 | 0.0 | ||||
(0.0) | (32.9) | (0.0) | (0.0) | (0) | ||||
100 | 8.9 | C 2 | 73.7 | 10.8 | 9.1 | 20.7 | 100 | |
(10.9) | (0.59) | (0.2) | (1.5) | (0) | ||||
C 3 | 69.1 | 8.2 | 9.2 | 37.5 | 100 | |||
(11.2) | (0.25) | (0.2) | (1.6) | (0) | ||||
9.9 | 119.7 | 1.0 | 0.2 | 0.0 | ||||
(0.6) | (16.9) | (0.2) | (0.0) | (0.0) | ||||
10 | 9.1 | C 2 | 102.2 | 10.5 | 9.0 | 22.1 | 99.9 | |
(14.2) | (0.7) | (0.1) | (1.5) | (0.7) | ||||
C 3 | 94.2 | 7.7 | 9.2 | 41.7 | 100 | |||
(13.2) | (0.2) | (0.1) | (1.4) | (0.0) | ||||
40.0 | 118.6 | 0.0 | 0.0 | 0.0 | ||||
(0.1) | (20.0) | (0.0) | (0.0) | (0.0) | ||||
2 | 40 | 9.1 | C 2 | 97.0 | 10.3 | 9.1 | 22.2 | 100 |
(12.0) | (0.5) | (0.1) | (0.4) | (0.0) | ||||
C 3 | 87.4 | 7.7 | 9.2 | 41.2 | 100 | |||
(12.9) | (0.2) | (0.1) | (1.2) | (0.0) | ||||
115.9 | 120.1 | 0.0 | 0.0 | 0.0 | ||||
(38.9) | (18.9) | (0.0) | (0.0) | (0.0) | ||||
200 | 8.6 | 95.3 | 72.7 | 1.6 | 3.7 | 16.7 | ||
(15.5) | (31.3) | (3.5) | (8.2) | (37.8) | ||||
C 3 | 118.5 | 8.9 | 9.3 | 31.2 | 100 | |||
(28.3) | (0.5) | (0.1) | (3.2) | (0.0) | ||||
14.6 | 86.2 | 0.26 | 0.09 | 0.0 | ||||
(1.14) | (14.1) | (0.31) | (0.11) | (0) | ||||
15 | 9.0 | C 2 | 103.9 | 9.0 | 8.4 | 22.1 | 99.6 | |
(11.8) | (0.13) | (0.48) | (1.5) | (1.1) | ||||
C 3 | 92.8 | 7.2 | 9.2 | 41.6 | 100 | |||
(10.7) | (0.77) | (0.13) | (1.4) | (0.0) | ||||
59.9 | 81.2 | 0.03 | 0.03 | 0.0 | ||||
(0.29) | (12.1) | (0.07) | (0.06) | (0) | ||||
3 | 60 | 8.9 | C 2 | 93.8 | 10.3 | 9.1 | 22.3 | 99.9 |
(12.3) | (0.43) | (0.13) | (1.4) | (0.3) | ||||
C 3 | 87.2 | 7.7 | 9.2 | 41.3 | 100 | |||
(11.4) | (0.16) | (0.13) | (1.3) | (0.0) | ||||
142.4 | 81.0 | 0.00 | 0.00 | 0.0 | ||||
(31.0) | (13.7) | (0.00) | (0.00) | (0) | ||||
300 | 8.4 | 157.5 | 54.6 | 0.03 | 0.04 | 0.0 | ||
(31.0) | (11.1) | (0.06) | (0.09) | (0) | ||||
C 3 | 119.2 | 8.9 | 9.4 | 30.3 | 99.9 | |||
(11.4) | (0.28) | (0.10) | (0.96) | (0.02) |
Evaluation of the second step of the ORdensity method with α=0.05. In the first column number of blocks. In column 2, the number of total simulated DE genes. In column 3, the 10×f0 values where f0 is the average proportion of permuted cases in sets Ui. In column 4, the “*” indicates the clusters considered by the procedure. Columns 5–8 contain for each cluster: the mean number of genes (), the mean of OR values (), the mean of FP values (), the mean of dFP values (). In the last column the mean of False Positives genes per cluster in % (). Corresponding standard deviations are in brackets