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. 2018 Sep 10;19:317. doi: 10.1186/s12859-018-2318-8

Table 7.

Simulation study 2, with nX=nY=30 and 100 runs

B DE 10f0 C i n¯i OR¯ FP¯ dFP¯ FPC¯
(sd) (sd) (sd) (sd) (sd)
C1 27.9 160.4 6.6 8.1 32.0
(31.2) (102.2) (1.1) (10.8) (43.9)
5 9.1 C 2 92.1 10.1 9.0 24.1 100
(25.5) (0.8) (0.4) (4.0) (0)
C 3 82.5 7.8 9.4 41.6 100
(17.9) (0.3) (0.3) (2.2) (0)
C1 20.0 233.0 0.0 0.0 0.0
(0.0) (35.1) (0.0) (0.0) (0)
1 20 9.1 C 2 96.5 10.4 9.0 22.0 100
(12.7) (0.5) (0.1) (1.5) (0)
C 3 90.1 7.7 9.2 41.1 100
(14.2) (0.2) (0.1) (1.4) (0)
C1 100.0 209.5 0.0 0.0 0.0
(0.0) (32.9) (0.0) (0.0) (0)
100 8.9 C 2 73.7 10.8 9.1 20.7 100
(10.9) (0.59) (0.2) (1.5) (0)
C 3 69.1 8.2 9.2 37.5 100
(11.2) (0.25) (0.2) (1.6) (0)
C1 9.9 119.7 1.0 0.2 0.0
(0.6) (16.9) (0.2) (0.0) (0.0)
10 9.1 C 2 102.2 10.5 9.0 22.1 99.9
(14.2) (0.7) (0.1) (1.5) (0.7)
C 3 94.2 7.7 9.2 41.7 100
(13.2) (0.2) (0.1) (1.4) (0.0)
C1 40.0 118.6 0.0 0.0 0.0
(0.1) (20.0) (0.0) (0.0) (0.0)
2 40 9.1 C 2 97.0 10.3 9.1 22.2 100
(12.0) (0.5) (0.1) (0.4) (0.0)
C 3 87.4 7.7 9.2 41.2 100
(12.9) (0.2) (0.1) (1.2) (0.0)
C1 115.9 120.1 0.0 0.0 0.0
(38.9) (18.9) (0.0) (0.0) (0.0)
200 8.6 C2 95.3 72.7 1.6 3.7 16.7
(15.5) (31.3) (3.5) (8.2) (37.8)
C 3 118.5 8.9 9.3 31.2 100
(28.3) (0.5) (0.1) (3.2) (0.0)
C1 14.6 86.2 0.26 0.09 0.0
(1.14) (14.1) (0.31) (0.11) (0)
15 9.0 C 2 103.9 9.0 8.4 22.1 99.6
(11.8) (0.13) (0.48) (1.5) (1.1)
C 3 92.8 7.2 9.2 41.6 100
(10.7) (0.77) (0.13) (1.4) (0.0)
C1 59.9 81.2 0.03 0.03 0.0
(0.29) (12.1) (0.07) (0.06) (0)
3 60 8.9 C 2 93.8 10.3 9.1 22.3 99.9
(12.3) (0.43) (0.13) (1.4) (0.3)
C 3 87.2 7.7 9.2 41.3 100
(11.4) (0.16) (0.13) (1.3) (0.0)
C1 142.4 81.0 0.00 0.00 0.0
(31.0) (13.7) (0.00) (0.00) (0)
300 8.4 C2 157.5 54.6 0.03 0.04 0.0
(31.0) (11.1) (0.06) (0.09) (0)
C 3 119.2 8.9 9.4 30.3 99.9
(11.4) (0.28) (0.10) (0.96) (0.02)

Evaluation of the second step of the ORdensity method with α=0.05. In the first column number of blocks. In column 2, the number of total simulated DE genes. In column 3, the 10×f0 values where f0 is the average proportion of permuted cases in sets Ui. In column 4, the “*” indicates the clusters considered by the procedure. Columns 5–8 contain for each cluster: the mean number of genes (n¯i), the mean of OR values (OR¯), the mean of FP values (FP¯), the mean of dFP values (dFP¯). In the last column the mean of False Positives genes per cluster in % (FPC¯). Corresponding standard deviations are in brackets