Table 1.
Characteristics of inflammatory bowel disease patients and controls in the case-control study
| IBD | Control | P value | |
|---|---|---|---|
| Total (n)b | 1392 | 1392 | – |
| Male (n) | 634 | 658 | 0.362 |
| Age (years)b | 37.0 ± 5.8 | 36.7 ± 5.8 | 0.454 |
| BMI (kg/m2)a | 23.2 ± 4.3 | 22.4 ± 4.3 | < 0.001 |
| History of smoking (n) | 604 | 296 | < 0.001 |
| History of drinking (n) | 410 | 395 | 0.531 |
| History of iodized salt intaking (n) | 754 | 708 | 0.081 |
| History of radiation exposure (n) | 251 | 14 | < 0.001 |
| History of benign thyroid nodule (n) | 1064 | 570 | < 0.001 |
| Family history of TC (n)a | 135 | 22 | < 0.001 |
| Age at diagnosis of IBD (years)a | 26.9 ± 6.3 | – | – |
| Duration of IBD on admission (years) | 10.1 ± 2.8 | – | – |
| Extraintestinal manifestations (n) | 708 | – | – |
| 5-ASA treatment (n)a | 1334 | – | – |
| PTC development (n)a | 11 | 3 | 0.032 |
aBMI Body mass index, IBD inflammatory bowel disease, 5-ASA 5-aminosalicylic acid, PTC papillary thyroid carcinoma, TC thyroid cancer
bCategorical and continuous variables were separately showed by frequency and mean ± standard deviation