Table 4.
Area under the ROC curve (AUROC) of significant variables regarding septic AKI and in-hospital mortality
| Variables | Septic AKI | In-hospital mortality | ||||||
|---|---|---|---|---|---|---|---|---|
| AUROC | P value | Cutoff value | Sensitivity/specificity (%) | AUROC | P value | Cutoff value | Sensitivity/specificity (%) | |
| Serum NGAL | 0.991 | < 0.001 | 413.2 | 92.3/100 | 0.768 | 0.021 | 385.3 | 75.0/64.3 |
| Urinary NGAL | 0.915 | 0.001 | 383.7 | 92.3/77.8 | 0.780 | 0.016 | 383.7 | 75.0/64.3 |
| Serum calprotectin | 0.889 | 0.002 | 219.8 | 84.6/88.9 | ||||
| Serum KIM-1 | 0.752 | 0.049 | 17.2 | 69.2/77.8 | ||||
| Urinary Cystatin C | 0.641 | 0.271 | 118.9 | 53.8/66.7 | ||||
| Albumin | 0.269 | 0.071 | 2.6 | 38.5/33.3 | 0.232 | 0.021 | 2.5 | 41.7/35.7 |
| Creatinine | 0.966 | < 0.001 | 0.9 | 100.0/88.9 | 0.676 | 0.129 | 0.9 | 75.0/57.1 |
| CRP | 0.795 | 0.021 | 82.4 | 76.9/77.8 | ||||
| SOFA score | 0.957 | < 0.001 | 7.5 | 92.3/88.9 | 0.774 | 0.018 | 7.5 | 75.0/71.4 |
| APACHE II Score | 0.842 | 0.008 | 13.5 | 76.9/77.8 | 0.762 | 0.024 | 15.0 | 66.7/71.4 |
| Serum NGAL+ Serum Calprotectin + SOFA score |
1.000 | < 0.001 | ||||||
| Serum NGAL + urinary NGAL + SOFA score | 0.911 | < 0.001 | ||||||
AKI acute kidney injury, NGAL neutrophil gelatinase-associated lipocalin, SOFA Sequential Organ Failure Assessment, APACHE Acute Physiology and Chronic Health Evaluation