Table 5. Physiological parameters and genotypic classes for lipoprotein lipase gene; -53 G<C promoter polymorphism in obese and non-obese subjects.
| Obese subjects | Non-obese subjects | |||||||
|---|---|---|---|---|---|---|---|---|
| GG (n = 283) |
GC (n = 14) |
CC (n = 12) |
GG (n = 304) |
GC (n = 26) |
CC (n = 3) |
GC+CC* (n = 26+3) |
||
| BMI | 33.2 ± 3.3 | 34.7 ± 4.4 | 36.7 ± 5.6 | 22.8 ± 3.3 | 23.8 ± 2.6 | 24.8 ± 3.0 | 26.7 ± 2.9 | |
| p-value | 0.002 | 0.017 | 0.004 | |||||
| Fasting glucose, mg/dL | 109.2 ± 18.5 | 116.9 ± 20.2 | 111.4 ± 16.9 | 112.4 ± 15.6 | 112.1 ± 15.5 | 116.4 ± 34.3 | 115.4 ± 17.7 | |
| p-value | 0.297 | 0.078 | 0.083 | |||||
| Fasting insulin, mU/mL | 13.7 ± 8.2 | 18.7 ± 11.3 | 33.9 ± 1.5 | 8.2 ± 4.8 | 9.3 ± 5.0 | 20.8 ± 6.6 | 19.5 ± 7.4 | |
| p-value | < 0.001 | < 0.001 | < 0.001 | |||||
| HOMA index | 3.8 ± 2.6 | 5.1 ± 3.1 | 9.8 ± 1.7 | 2.5 ± 1.5 | 2.8 ± 2.4 | 5.9 ± 2.0 | 5.6 ± 2.2 | |
| p-value | < 0.001 | < 0.001 | < 0.001 | |||||
| Percentage body fat | 36.9 ± 6.1 | 40.2 ± 5.1 | 41.3 ± 5.8 | 26.6 ± 6.1 | 29.8 ± 5.9 | 31.7 ± 4.7 | 30.9 ± 5.7 | |
| p-value | 0.008 | 0.014 | 0.022 | |||||
| FM, kg | 30.2 ± 8.1 | 34.3 ± 9.7 | 34.2 ± 10.0 | 20.3 ± 8.2 | 20.3 ± 7.2 | 20.3 ± 4.7 | 22.9 ± 7.0 | |
| p-value | 0.059 | 0.250 | 0.111 | |||||
Data presented as mean±SD.
HOMA index: homeostasis model assessment index; FM: fat mass; BMI: body mass index.